Dr. Nguyen Thi Mong Diep and her research team have successfully developed recombinant eCG and hFSH hormones for the entire reproductive support process with just a single injection. These new hormones, produced through a combination of genetic engineering and biotechnology, offer a more effective, sustainable, and accessible infertility treatment option compared to traditional products.
The project was funded by the Vingroup Innovation Fund (VINIF) in November 2020, and the team successfully launched two hormones – eCG and hFSH – by April 2024. The biological effectiveness of these hormones is nearly equivalent to standard hormones, with the advantage of a long half-life in the body that requires only a single injection for the entire treatment process.
Associate Professor Mong Diep highlighted the scarcity of natural gonadotropin hormones and the challenges in production and supply due to hygiene and ethical issues. This scarcity has led to high transportation costs, increasing the overall cost of natural gonadotropin hormones, affecting their use in infertility treatments for humans and reproductive control in animals.
The project’s recombinant single-chain hormones offer a solution to this problem, providing a more effective, sustainable, and accessible infertility treatment option compared to traditional products. Clinical trials on humans have not yet been conducted due to current project limitations, but the research team is prepared to transfer the technology for market implementation.
Experts at a recent scientific conference held at Quy Nhon University praised the potential and effectiveness of these two single-chain recombinant hormones in modern assisted reproductive techniques. The research is believed to significantly support fertility in humans and animals, with a specific focus on improving cattle reproduction. Dr. Huynh Gia Bao, an expert in IVF techniques, hopes that this research project will enhance accessibility and reduce treatment costs for Vietnamese patients, particularly in remote areas.
Associate Professor Dr. Nguyen Thi Mong Diep is head of the Department of Applied Biology – Agriculture at Quy Nhon University collaborates on research with INRAe (the French National Institute for Research on Agriculture Food Environment). Her recent achievement as only Vietnamese person meeting professor standards in France highlights her significance contributions to biotechnology field
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